New treatment cuts bad cholesterol by nearly 50% without statins

A new breakthrough could change how high cholesterol is treated, offering a powerful alternative to traditional drugs. Researchers have developed tiny DNA-based molecules that shut down PCSK9—a key protein that keeps “bad” LDL cholesterol circulating in the blood. By blocking this protein, cells can absorb more cholesterol instead of letting it build up in arteries, dramatically lowering levels linked to heart disease.